According to researchers from the Universitat Rovira i Virgili, thanks to an extract present in grape seeds, it could protect the intestinal function from the alterations associated with obesity.
The study was carried out by a team of researchers from the Department of Biochemistry and Biotechnology of the Rovira i Virgili University. Researchers have found a relationship between some flavonoids called proanthocyanidins, which are extracted from the grape seed, reaching the conclusion that administered in different doses can protect from alterations in intestinal function associated with obesity.
Previously these researchers had already shown, in studies with rats, that the so-called "coffee shop diet", composed of processed foods rich in saturated fatty acids, cholesterol and refined sugars, causes intestinal inflammation, oxidative stress and alterations of the intestinal barrier.
The study was conducted with five groups of rats: one received a standard diet and the other four were fed "coffee shop diet" for fifteen weeks. At the end of this period the animals fed "coffee shop diet" were already obese and three of the four groups received a supplementation with daily doses of grape bone proanthocyanidins for three more weeks. When this stage was completed, bowel function was analyzed in all animals, with special attention to oxidative stress, inflammation and the function of the intestinal barrier.
The results showed that grape seed extract has an antioxidant and anti-inflammatory effect when it comes to improving and correcting the intestinal alterations of animals that had received a diet high in fats and in refined sugars, since it is managed to reduce intestinal oxidative stress, intestinal inflammation and could also have a protective effect against the deterioration of the intestinal barrier function.